

Currently, HCQ, which is far less toxic than chloroquine, continues to be used as an antimalarial drug and in the treatment of connective tissue diseases worldwide. The 4-aminoquinolone compounds, chloroquine and hydroxychloroquine sulfate (HCQ), have long been used to treat connective tissue disorders, most specifically rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Additionally, the average area of each scotoma detected by all three methods expanded from 34.5 square degrees of central field loss on AG testing to 71 square degrees on RAG and 117 on TAG.Ĭonclusion: By decreasing the perceived luminance of the suprathreshold AG, TAG testing provides a novel alternative to detect shallow scotomas and areas of depressed retinal activity secondary to HCQ toxicity.

Among patients who had been treated with HCQ, AG revealed scotomas in two of 56 (3.64%) patients in contrast, six (10.7%) and 37 (66.1%) scotomas were identified by RAG and TAG testing respectively. Results: No scotomas were observed in patients never treated with HCQ. Methods: 56 rheumatological patients taking HCQ and 12 similar patients not taking HCQ were tested by AG, red Amsler grid (RAG), and TAG. The aim of this study was to determine if the threshold Amsler grid (TAG) test, which varies light transmission through two cross polarising filters, allows increased detection of scotomas caused by HCQ toxicity. However, AG is a suprathreshold target and may not detect relative central scotomas. Currently, the standard Amsler grid (AG) is one of the most useful methods to identify such lesions. Mark areas of the chart you’re not seeing properly (print two charts if you notice problems in each eye) and bring it with you when you visit your doctor.Background/aims: Patients taking hydroxychloroquine (HCQ) are at risk of developing classic bull’s eye maculopathy.


#Amsler grid download
This free download is designed to help you determine the health of your retina. The Amsler grid is a tool that eye doctors use to detect vision problems resulting from damage to the macula (the central part of the retina) or the optic nerve.
#Amsler grid how to
How to test your eyes with this Amsler Grid:
